Hypertension and Stroke Pathophysiology and Management

Stroke is the third leading cause of death in the US and a leading cause of disability among adults. Stroke is not an accident but occurs in relation to a number of risk factors or antecedents. Hypertension is the most important modifiable risk factor for stroke, and blood pressure level may play an important role in determining outcome after acute ischemic or hemorrhagic stroke. Hypertension remains poorly controlled in the community at-large, and once stroke occurs clinicians are not certain about proper management of blood pressure during the acute, subacute and chronic periods after stroke. Given the importance placed on hypertension as a risk factor for stroke and new data which is now available from clinical trials regarding management of hypertension for stroke prevention and after stroke, a compendium is needed to concisely summarize the available data on hypertension and stroke and direct clinicians about proper treatment of blood pressure.

This text will address the epidemiology, mechanism, and pathophysiology of hypertension and blood pressure in relation to stroke and other brain sequelae of abnormal blood pressure, results of clinical trials demonstrating best suggested practice modalities to manage blood pressure and hypertension, and provide practical management tips for controlling blood pressure and hypertension. The book will be a valuable asset to medical students, resident physicians, practicing physicians, and other health care professionals who treat stroke patients or deal with persons at high-risk for stroke.