Drug Discovery and Evaluation Pharmacological Assays

This reference book contains a comprehensive selection of the most frequently used assays for reliably detecting pharmacological effects of potential drugs including cardiovascular, analgesic, endocrine, psychotropic, respiratory, renal, and immunomodulatory activities. Each of the over 700 assays comprises a detailed protocol with the purpose and rationale of the method, a critical assessment of the results and their pharmacological and clinical relevance. Identification of specific tests is facilitated by the enclosed CD-ROM which allows for a quick full-text research. An appendix with guidelines and legal regulations for animal experiments in various countries will help to plan experiments properly in accordance with the welfare of the laboratory animals.