Brain Control of Wakefulness and Sleep

Updating the 1990 first edition of this work, the second edition continues to intertwine what is known about the basic cellular physiology and anatomy of sleep and wakefulness with behavioral and physiological studies. Steridade (Universite Laval, Canada) and McCarley (Harvard Medical School) chose to author the work rather than prepare a compendium of contributed papers so that the material is presented with extraordinary coherence, with acknowledged emphasis on the work they know best (their own) and a conscious choice to omit areas of research that have been recently reviewed elsewhere. They begin with review of the changing concepts of mechanisms of waking and sleep states and of morphological, electrophysiological, and noninvasive methods of study. Coverage proceeds through afferent and efferent connections of brainstem and forebrain modulatory systems, neuronal circuits and electrophysiological properties of various parts of the brain; REM sleep; and sleep control. Cross references throughout.