Acute Promyelitic Leukemia Molecular Genetics, Mouse Models and Targeted Therapy
Description
Over the past 10 years, work on acute promyelocytic leukemia (APL) has become the paradigm of translational research that began with the discovery of a recurrent chromosomal translocation, followed by the identification of the genes and proteins involved, finding their molecular functions in transcriptional control, establishing mouse models and culminating in the development of targeted therapy.
Keywords
MedicalOncology
2006Book
Author(s)P. K. Vogt
PublisherSpringer Berlin Heidelberg
ISBN9783540345923
LanguageEnglish
