Paratuberculosis Organism, Disease, Control

This book discusses the history, prevalence, economic costs, disease control, diagnosis, vaccine development, aetiological agent, and control programmes of paratuberculosis in ruminants. Topics discussed are: history of paratuberculosis; prevalence and economics of infection of Mycobacterium avium subsp. paratuberculosis; epidemiology of Mycobacterium avium subsp. paratuberculosis; Mycobacterium avium subsp. paratuberculosis in animal-derived foods and environment; paratuberculosis and Crohn's disease; genetics of host susceptibility to paratuberculosis; Mycobacterium avium complex; Mycobacterium avium subsp. paratuberculosis genome, molecular genetics, proteome and antigens; host-pathogen interactions and intracellular survival of Mycobacterium avium subsp. paratuberculosis; comparative differences between the strains of Mycobacterium avium subsp. paratuberculosis; antibacterial agents against paratuberculosis; paratuberculosis in cattle, sheep, goats, deer, camelids, other ruminants and non-ruminant wildlife; experimental ruminant and small animal models of paratuberculosis; immunology of paratuberculosis infection and disease; cultivation of Mycobacterium avium subsp. paratuberculosis; diagnosis of paratuberculosis by PCR; immune-based diagnosis of paratuberculosis; strain characterization of Mycobacterium avium subsp. paratuberculosis; paratuberculosis control measures in Europe, USA and Australia; ruminant aspects of paratuberculosis vaccination; and development of new paratuberculosis vaccines. This book is intended for epidemiologists, veterinarians, farm owners and managers, wildlife practitioners, geneticists and students.