Genetics and Probability in Animal Breeding Experiments A Primer and Reference Book on Probability, Segregation, Assortment, Linkage and Mating Systems for Biomedical Scientists who Breed and Use Genetically Defined Laboratory Animals for Research

Probability and statistics: Variables and probabilities; Segregation of alleles:Experiment 1: matings of pale eared and normal eared mice; proportions and probabilities; inferences, symbols and assumptions; Assortment of non-alleles: experiment 2: matings of mice with pale ears and dilute coats; Symbols; Gametic output; Mating types; Inference; Linkage, recombination and mapping: Experiment 4: matings of mice with pale ears and ruby eyes; Definitons and symbols;Mating systems: Experimental designs; Appendix 1: Mean and variance of a binomial distribution; Appendix2 : Estimation of a parameter by the method of maximum likelihood; Appendix 3: Extensions of the method of maximum likelihood; Appendix 4: Comparative efficiency of matings for detecting and measuring linkage; Appendix 5; The fibonacci sequence; Appendix 6 ; systems of mating; Appendix 7: Numbers of matings and numbers of mice per mating; Appendix 8: nomenclature; Appendix 9: Record-keeping; Appendix 10 Mouseroom layout and procedures; Index.