Nisoldipine 1987 With 151 Figures and 72 Tables

This book, the first to provide a comprehensive overview of all studies so far carried out with this second-generation calcium entry blocker, Nisoldipine, is the fruit of a- day conference. In the first part the essential data on its experimental and clinical pharmacology are summarised by outstanding research workers in this field. The second part contains work concerning the major action of the drug, namely its effect in reducing vasomotor tone. The third part deals with intravenous or oral administration. From these data a clear profile develops, which is effective in angina pectoris of various forms and in cardiac ischaemia, both the clinically evident and the silent forms. Additionally, exploratory data in the area of cardiac failure are presented. As several contributors are based on material presented as a poster they do not contain a reference list. This book is highly recommended for all those investigators and clinicians who are researching for the optimal calcium entry blocker.