Enzymology and Molecular Biology of Carbonyl Metabolism 7 [Proceedings of the 9th International Symposium on Enzymology and Molecular Biology of Carbonyl Metabolism, Held June 20-24, 1998, in Varallo Sesia, Vercelly, Italy]

Aldehyde Dehydrogenasé.- 1. The Big Book of Aldehyde Dehydrogenase Sequences: An Overview of the Extended Family.- 2. Reaction-Chemistry-Directed Sequence Alignment of Aldehyde Dehydrogenases.- 3. Three-Dimensional Structure of Mitochondrial Aldehyde Dehydrogenase: Mechanistic Implications.- 4. A Structural Explanation for the Retinal Specificity of Class 1 ALDH Enzymes.- 5. Structure and Function of Betaine Aldehyde Dehydrogenase: An Enzyme within the Multienzyme Aldehyde Dehydrogenase System.- 6. Evaluation of the Roles of the Conserved Residues of Aldehyde Dehydrogenase.- 7. Aldehyde Dehydrogenase Catalytic Mechanism: A Proposal.- 8. Inhibition of Human Mitochondrial Aldehyde Dehydrogenase by Metabolites of Disulfiram and Structural Characterization of the Enzyme Adduct by HPLC-Tandem Mass Spectrometry.- 9. Mechanism of Inhibition of Rat Liver Class 2 ALDH by 4-Hydroxynonenal.- 10. Aldehyde Inhibitors of Aldehyde Dehydrogenases.- 11. Covalent Modification of Sheep Liver Cytosolic Aldehyde Dehydrogenase by the Oxidative Addition of Coloured Phenoxazine, Phenothiazine and Phenazine Derivatives.- 12. A Thioester Analogue of an Amino Acetylenic Aldehyde Is a Suicide Inhibitor of Aldehyde Dehydrogenase and an Inducer of Apoptosis in Mouse Lymphoid Cells Overexpressing the bcl2 Gene.- 13. Reaction between Sheep Liver Mitochondrial Aldehyde Dehydrogenase and a Chromogenic 'Reporter Group' Reagent.- 14. Activity of the Human Aldehyde Dehydrogenase 2 Promoter Is Influenced by the Balance between Activation by Hepatocyte Nuclear Factor 4 and Repression by Perosixome Proliferator Activated Receptor ?, Chicken Ovalbumin Upstream Promoter-Transcription Factor, and Apolipoprotein Regulatory Protein-1.- 15. a, ?-Unsaturated Aldehydes Mediate Inducible Expression of Glutathione S-Transferase in Hepatoma Cells through Activation of the Antioxidant Response Element (ARE).- 16. Effect of Arachidonic Acid Alone or with Prooxidant on Aldehyde Dehydrogenases in Hepatoma Cells.- 17. Prepubertal Regulation of the Rat Dioxin-Inducible Aldehyde Dehydrogenase (ALDH3).- 18. Effects of Tamoxifen and Toremifene on ALDH1 and ALDH3 in Human Retinal Pigment Epithelial Cells and Rat Liver.- 19. Negative Regulation of Rat Hepatic Aldehyde Dehydrogenase 3 by Glucocorticoids.- 20. Modulation of Class 3 Aldehyde Dehydrogenase Gene Expression: An Eye Opening Experience.- 21. Susceptibility of Hepatoma Cells to Lipid Peroxidation and Adaptation of ALDH 3C Activity to Iron-Induced Oxidative Stress.- 22. The Lack of AHD4 Induction by TCDD in Corneal Cells May Involve Tissue-Specific Regulatory Proteins.- 23. Human Corneal and Lens Aldehyde Dehydrogenases: Localization and Function(s) of Ocular ALDH 1 and ALDH3 Isozymes.- 24. The Role of Retinoid Metabolism by Alcohol and Aldehyde Dehydrogenases in Differentiation of Cultured Neuronal Cells.- 25. Metabolism of Retinaldehyde by Human Liver and Kidney.- 26. The Hunt for a Retinal-Specific Aldehyde Dehydrogenase in Sheep Liver.- 27. Cardiac Metabolism of Enals.- 28. Oxidation of Ethanol to Acetaldehyde in Brain and the Possible Behavioral Consequences.- 29. Cloning and Expression of a cDNA Encoding a Constitutively Expressed Rat Liver Cytosolic Aldehyde Dehydrogenase.- 30. The Roles of Acetaldehyde Dehydrogenases in Saccharomyces Cerevisiae.- 31. Characterization of an Aldehyde Dehydrogenase Gene Fragment from Mung Bean (Vigna radiatd) Using the Polymerase Chain Reaction.- 32. Aldehyde Dehydrogenase Gene Superfamily: The 1998 Update.- Alcohol Dehydrogenase.- 33. Human Alcohol Dehydrogenase Family: Functional Classification, Ethanol/Retinol Metabolism, and Medical Implications.- 34. Dynamics in Alcohol Dehydrogenase Elucidated from Crystallographic Investigations.- 35. Studies on Variants of Alcohol Dehydrogenases and Its Domains.- 36. Uncompetitive Inhibitors of Alcohol Dehydrogenases.- 37. Tandem Mass Spectrometry of Alcohol Dehydrogenase and Related Biomolecules.- 38. Function of Alcohol Dehydrogenase and Aldehyde De